Osafa Chram was a Bene Gesserit sister who attempted to assassinate New Sisterhood Mother Commander Murbella at a planet-wide conference called during the advent of Kralizec. As it became apparent that the great Outside Enemy that human-kind was squaring off against was of utmost power, Murbella decided to call all active Sisterhood personnel to a large conference at the Chapterhouse Keep. As the sisters assembled in their seats, the last one roaming the aisleways to find a seat was Chram. As Murbella began to confront her for her tardiness, Osafa brandished a Crysknife, and lunged at Murbella. Murbella deftly moved out of the way, and came up swinging with a counter-attack that broke Chram's arm, then her larynx.