The Battle of Ceresole (or Cérisoles) was an encounter between a French army and the combined forces of Spain and the Holy Roman Empire during the Italian War of 1542–46. The lengthy engagement took place on 11 April 1544, outside the village of Ceresole d'Alba in the Piedmont region of Italy; the French, under François de Bourbon, Count of Enghien, defeated the Spanish-Imperial army of Alfonso d'Avalos d'Aquino, Marquis del Vasto. Despite having inflicted substantial casualties on the Imperial troops, the French subsequently failed to exploit their victory by taking Milan.