Spider-Man of Earth-20080522 was almost exactly the same as his Earth-616 counterpart until the alien symbiote corrupted him and completely bonded itself to him. Spider-Man became more murderous and married the Black Cat. He was the most recent addition to Captain Anarchy's Revengers. He fought his Earth-616 counterpart when the Revengers faced off against the Avengers of that reality, and stood by a completely insane Captain Anarchy later on. However, Anarchy killed him for threatening Earth-616's Scarlet Witch.