Azakai was an only child born to Aburame Miyuki (Mother) and Aburame Hisoka (Father). Azakai had a natural talent for tactical and strategic planning and this is what made her a candidate for the infiltration team that Danzo was trying to put in order. At the age of 11 Azakai 'graduated' from the academy and was taken into an infiltration training program. Both of Azakai's parents opposed the idea however Danzo mentioned that other clans such as the Inuzuka and Hyuga were also sending in people so Azakai accepted the position herself despite her parents protests.