Laudanol is the name of a government-created new drug, first seen in "Chuck Versus the Tic Tac", which has been designed by the CIA to remove the emotions of whoever takes it. It was originally intended to be given to American soldiers, so that they are able to able to perform better in battles, making them fearless and maybe even removing pain. Chuck asks if the pill would work for him, as it is the presence of this emotional turmoil which is causing the Intersect 2.0 to not function properly.