USNS Guadalupe (T-AO-200) is a Henry J. Kaiser-class underway replenishment oiler operated by the Military Sealift Command to support ships of the United States Navy. Guadalupe, the fourteenth ship of the Henry J. Kaiser class, was laid down at Avondale Shipyard, Inc., at New Orleans, Louisiana, on 9 July 1990 and launched on 5 October 1991. She entered non-commissioned U.S. Navy service under the control of the Military Sealift Command with a primarily civilian crew on 25 September 1992. She serves in the United States Pacific Fleet.