An entheogen ("creates god within," en εν- "in, within," theo θεος- "god, divine," -gen γενος "creates, generates"), in the strict sense, is a psychoactive substance used in a religious, shamanic or spiritual context. Historically, entheogens were mostly derived from plant sources and have been used in a variety of traditional religious contexts. Most entheogens do not produce drug dependency. With the advent of organic chemistry, there now exist many synthetic substances with similar psychoactive properties. Entheogens are tools to supplement various practices for healing and transcendence, including in meditation, psychonautics, art projects, and psychedelic therapy.