Lost and alone in unknown territory, astronaut John Crichton has found a refuge of sorts aboard Moya, a vast living starship sheltering a fractious band of bizarre alien fugitives. Now Moya and her squabbling inhabitants have run afoul of a mysterious space vessel that only seems to be deserted. In truth, the ship belongs to a race of strange astral entities who lure the unlucky wayfarers into their clutches. Desperate to fulfill an ancient prophecy, the crew of the "ghost ship" will stop at nothing to escape their limbo-like existence, forcing Crichton and the others to brave the mystic terrors of an alien realm in order to free the restless spirits - not to mention themselves!