"Uptown" was the lead single in the U.S. to Prince's third album, Dirty Mind. Beginning with a lone drum intro, the track explodes into the keyboards of the chorus. The verses feature a more prominent funk guitar. The song breaks down to a more instrumental section toward the end that is mainly guitar, bass and drums with an occasional keyboard riff. The minimalist style of the song is representative of most of the Dirty Mind album. The song addresses the Uptown neighborhood of Minneapolis that was the city's hang-out spot for artists.