USS Falmouth was a sloop of war in the United States Navy during the mid-19th century. Falmouth was launched on 3 November 1827 by Boston Navy Yard, and declared ready for sea 19 January 1828, Commander C. W. Morgan in command. Between 1828 and 1840, Falmouth made two cruises with the West Indies Squadron and two with the Pacific Squadron. Between cruises, she was in ordinary for repairs and refittings at either New York or Norfolk or Norfolk Navy Yard.