Thomas' sister was Dolores and his two brothers were Gambino crime family associate Robert DeSimone and Gambino associate Anthony DeSimone, murdered by mobster Thomas Agro in 1979. He was the brother-in-law of mobster Joseph "The Barber" Spione, who was slain for refusing to help kill DeSimone in the late 1970s. His sister Phyllis was Jimmy Burke's mistress since she was sixteen years old. He is the ex-father-in-law of Gambino crime family associate Salvatore DeVita.