A traveling medicine man who's running from his past as a doctor, encounters and befriends Hoss. The doctor must come to terms with what happened on an operating table when an angered widow hunts him down. The woman mistakenly shoots Hoss instead, forcing the ex-doctor to practice medicine once more. Suffering from an infected foot, Hoss finds unexpected relief from Professor Poppy, an itinerant patent medicine peddler who secretly carries a medical bag.