Thomas Sydserf [Sydserff] (1581 – 1663) was a 17th century Scottish prelate. The eldest son of an Edinburgh merchant, Sydserf graduated from the University of Edinburgh in 1602 before travelling to continental Europe to study at the University of Heidelberg. After returning to Scotland, he entered the ministry, beginning at St Giles' parish, Edinburgh in 1611. 15 years later, in 1626, he was translated to Trinity College church, Edinburgh, before being admitted Dean of Edinburgh on February 19, 1634.