She got her start in acting at the age of 5 doing theater productions. She was later discovered and starred regularly in the WB's Nick Freno: Licensed Teacher. Later she had guest spots on Mad About You, 7th Heaven, The West Wing (in "The Stackhouse Filibuster"), Strong Medicine, and ER. She has also starred in several TV movies and had minor roles in several motion pictures such as Sleepless in Seattle and Avalon. She also starred in some Mary-Kate Olsen and Ashley Olsen Productions, such as You're Invited to Mary-Kate and Ashley's Sleepover Party, singing a song called "Gimme Pizza!" and the popular line "whipped cream pouring like waterfalls!" At this stage in her career, DeLizia was known for her high-pitched voice and pixie haircut.