Straiton has also directed such UPN series as Special Unit 2 and Kevin Hill and such science fiction series as Odyssey 5 (starring Peter Weller and created by Manny Coto) and The 4400 (starring Billy Campbell and co-created by René Echevarria). His other credits include Dawson's Creek, Dark Angel, Charmed, Angel, Dead Like Me, Cold Case, Las Vegas, House, and Hans Beimler and Robert Hewitt Wolfe's The Dresden Files.