Isaac enters the Crypt, a burial place for members of the Church of Unitology. The bodies are stored in cryogenic chambers, some of which contain Necromorphs that will burst forth and attack Isaac as he walks past them. Isaac eventually reaches a large chamber where he is attacked by a female Tripod, The Pack, Slashers, Exploders, and Pukers. After defeating a crawling Stalker and passing through a chamber with a Marker replica, Isaac reaches Daina.