The Diocese of South Florida was a diocese of the Episcopal Church in the United States of America, which was created in 1922 out of what had been the Missionary Jurisdiction of Southern Florida, sometimes called the Missionary District of Southern Florida, which had been split off in 1892 from the Diocese of Florida. Its northern line was the southern boundaries of the counties of Levy, Alachua, Putnam and St. Johns and covered the southern two-thirds of the Florida peninsula. Its see city was Orlando. In 1969, it was divided into three new dioceses as follows: the Diocese of Central Florida with its see at Orlando, the Diocese of Southeast Florida with its see at Miami and the Diocese of Southwest Florida, with its see at St. Petersburg.