The 2010 Pittsburgh Panthers football team represented the University of Pittsburgh in the 2010 NCAA Division I FBS football season. The Panthers were members of the Big East Conference. They were led by the sixth year head coach Dave Wannstedt and played their home games at Heinz Field. 2010 marked the University's 121st season overall. They finished the season 8–5, 5–2 in Big East play to be champions of the Big East with Connecticut and West Virginia. However, due to loses to both schools, Pitt did not earn the conferences bid to a BCS game. They were invited to the BBVA Compass Bowl where they defeated Kentucky 27–10. Head coach Dave Wannstedt was forced to resign on December 7, 2010.