Insignificance is a 1985 British comedy-drama film directed by Nicolas Roeg, produced by Jeremy Thomas and Alexander Stuart, and adapted by Terry Johnson from his play of the same name. The film is set in 1954, with most of the action taking place in a hotel room in New York City. The action revolves around the interplay of four characters who represent iconic figures of the era, Marilyn Monroe, Joseph McCarthy, Joe DiMaggio, and Albert Einstein called The Actress, The Senator, The Ballplayer, and The Professor, respectively.