A evil copy of Crash known as Titan Crash came to N.Sanity Island with along of other copies of Crash's friends and enemies and wreaked it and made their own games. Meanwhile, Crash and Aku Aku are locked in the ancient chambers of Naughty Dog. One day, a huge explosion goes off and it wakes up Crash and Aku Aku and they escape the chambers and throw the Titan characters into Twinsanity Island. While Crash and Aku Aku serach for the other classic characters, the classic Dr. Cortex is back and eviler than ever...