The 2004 Louisville Cardinals football team represented the University of Louisville in the 2004 college football season. The team, led by Bobby Petrino in his second year at the school, played their home games in Papa John's Cardinal Stadium. They finished 11–1 and were the Conference USA champions with a perfect 8-0 conference record in their last season before leaving to join the Big East Conference. They were invited to and won the Liberty Bowl, defeating Western Athletic Conference champion Boise State 44–40.