Gramma is the maternal grandmother of Greg, Rodrick and Manny Heffley and their twin cousins Malvin and Malcolm, and the mother of Susan Heffley, Aunt Cakey, Aunt Veronica, Aunt Audra and Aunt Gretchen. She tends to favor Manny, but she denies this. According to Greg in the online version, she has many photos of Manny and only has one of Greg's head from the back and none of Rodrick. She was married to Grampa, whom she either divorced or is a widow of.