Understanding this system is the key to the Hyuga Clan's Gentle Fist fighting style which forces chakra into an opponent's chakra pathway system. Proper application uses the system as a conductor sending harmful chakra directly to vulnerable vital organs. As there is no way to train a person's organs to resist physical or energy attack this method of fighting is extremely effective. An analogy could be made to being attacked with a tazer. Though Neji and more advanced users are known for attacking tenketsu, basic Gentle Fist is also extremely powerful as the chakra forced into the chakra pathways need not be specific as it effects everything in its vicinity. By using Gentle Fist, Neji was able to damage Hinata's heart to the extent that she was still coughing up blood a month later.