The naval Battle of Zonchio (, also known as the Battle of Sapienza or the First Battle of Lepanto) took place on four separate days: August 12, 20, 22 and 25, 1499. It was a part of the Ottoman–Venetian War of 1499–1503. It was the first naval battle in history where cannons were used on ships. On the second day, Grimani ordered the crews to kill any captains who refused to fight. Despite this, and the arrival of 4 French Galleys he sent just 2 galleys out of 170 against the Ottomans. Both somehow returned unharmed.