Spiritus Sancti is the bloodline discipline practiced by the Mystikoi, a Bloodline of Clan Gangrel that practices a form of Gnostic Christianity. Using Spiritus Sancti, the Mystikoi believe they can find the immaterial truths in this material world, using their Beasts as intermediaries between themselves and the divine Unity. For more details, purchase the Ancient Bloodlines sourcebook for Vampire: the Requiem.