The Pacific War was an enormously destructive conflict waged between the American-led Allied Powers and the Japanese-led Asian Powers between 1924 and 1929. The war resulted in the deaths of an estimated 65 million people and left nearly 200 million wounded or destitute, and required significant rebuilding for all the parties involved. The war was also significant for its new use of vicious and deadly technology, including poison gas, targeting of civilians and aerial warfare. The Pacific War was largely contained to the North Pacific, but battles and skirmishes erupted in the south Pacific.