The son of Destro, Alexander McCullen, used nanomites to infect his father and render him immobile and hidden away, thus, allowing Alexander to masquerade as him. Upon staging a coup on Cobra, he used the same nanomites to put Cobra Commander in a hallucinatory and docile state. He then had the nanomites tweaked with a more destructive capability in a bid to take over Washington D.C.. It took every resource the Joes could muster to find a way to stop him and his mad plan.