Chloe Sullivan and Tess Mercer began to interact after Tess had arrived in Smallville, taking possession of the Luthors' legacy following the disappearance of Lex Luthor. From the start, Chloe never trusted Tess, since she saw her as a potential enemy due to her being an ally of the Luthors. However, as time passed, Chloe began to see her that her true allegiances were lying with Clark and his Justice League, leading to their alliance and eventually, friendship.