Kyriakoulis Argyrokastritis (; died 1828) also known as Kyriakoulis Polychronis was a Greek resistance leader of the Greek War of Independence. He was born in Gjirokastër (Argyrokastron in Greek, his name means 'from Gjirokastër'), modern Albania, when the town was under Ottoman rule. Argyrokastritis joined the Greek revolution and in January 1828 together with the resistance leader Hatzimichalis Dalianis, from Delvinaki, landed on the island of Crete to support the revolution there.