The .50-110 Winchester (also known as the .50-100-450 Winchester, with different loadings) is an obsolete American black powder centerfire rifle cartridge. Introduced in 1899 for the Winchester Model 1886 repeater, the .50-110 Winchester was also available in single-shot weapons such as the Winchester 1885 Hi-Wall. Slight variations in charge weight in the same case led to the mistaken belief these were different rounds, when in fact they were not.