Following the events of Puppet Master 4, Rick Myers has been arrested under the suspicion of having caused the murders which occurred in the previous film. His boss, Dr. Jennings, gets him out on bail. In the storage of the police department. Blade has been put in a crime scene bag. He rips from the bag and jumps into Susie's purse. Dr. Jennings wants to go to the hotel and find the puppets that Rick has mentioned. He hires three thugs to break into the hotel. At Susie's house, Rick, who was sleeping at Susie's, is awakened by Blade and Rick knows that somethings not right with the hotel. In the underworld Sutekh puts him self into his last and most powerful Totem. The Totem comes out of the portal board and hides in the puppet trunk. When Rick shows up he finds the puppets and they all me