The monastery was founded by Saint Pishoy in the fourth century AD. On 13 December 841 AD (4 Koiak) 557 AM, Pope Joseph I fulfilled the desire of Saint Pishoy and moved his body as well as that of Saint Paul of Tammah to this monastery. Up to that date, the bodies of the two saints were at the monastery of Saint Pishoy at Deir el-Bersha. Today, the two bodies lie in the main church of the Coptic Orthodox Monastery of Saint Pishoy in the Nitrian Desert.