John James McCook (1806 – October 11, 1865), was a patriarch of the Fighting McCooks, one of the most prolific families in United States Army history. Five of his sons became prominent soldiers, chaplains, or sailors, as well as eight of his nephews. He served as a volunteer surgeon in the Union Army during the Civil War. He died just after its close at the headquarters of his son, General Anson G. McCook, in Washington, D. C., during a visit. McCook was buried at Steubenville beside his wife, who had preceded him in death by just six months.