As part of the Treaty of Boulogne which ended the war of the Rough Wooing, Claude, Marquis of Mayenne, was one of six French hostages sent to England. After their father died on 12 April 1550, Claude was allowed to come to Scotland, with a passport from Edward VI dated 11 May, to see his sister Mary of Guise and wrote from Edinburgh on 18 May that he would view the strong places of the realm. On August 1, 1547, he married Louise de Brézé (c. 1518 – January 1577), Lady of Anet, the daughter of Louis de Brézé, seigneur d'Anet, and Diane de Poitiers. They had eleven children: