One other possible theory about the disease is that, in fact, it only affects people with particularly large noses. This may be because of the excess heat transferred by the larger nasal surface area causes an increase of sweat and tension, making friction against the surrounding skin, leading to prolonged irritation and skin nerve cell malformation, then to high sensitivity and repetitive nasal scratching, ultimately then progressing to skin flake detachment and redness, then eventually leading to this disease. However, it could also be a coincidence and is therefore nothing to worry about. Doctors are keen to stress that people with big noses are not necessarily going to suffer from this disease at all.