On 12 March 1811, she was part of Bernard Dubourdieu's squadron sailing to raid the British commerce raider base of the island of Lissa. The squadron encountered William Hoste's frigate squadron, leading to the Battle of Lissa. Danaé was damaged by HMS Volage and had to retreat to Lesina for repairs. In the night of 4 September 1812, she exploded in the harbour of Trieste.