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The outer ring of the wheel menu has an orange background, and contains 11 hydrophobic amino acids. These amino acids are most likely to be found inside the protein, away from water. Hydrophobic amino acids on the outside of a protein are known as exposeds, and score poorly in Foldit. The inner ring has a blue background, and contains nine hydrophilic amino acids. These amino acids are more likely to be found on the outside of a protein.

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