The Ionite Nebula Region is an area of star systems covered by the massive Ionite Nebula, including Luria, homeworld of the Lurians, and the Federation also suspects the Lethean homeworld of being located here. Since the region is not controlled by a central government, the nebula is often inhabited by criminals hiding with relative safety. The Federation has given aid to some of the local governments to try and solve this problem, but their efforts have thus far been met with little success. (Last Unicorn RPG module: Star Trek: Deep Space Nine - Core Game Book)