Main_Page > Vampire: The Requiem > Bloodlines Bloodlines are small groups of related vampires in a given clan whose blood has changed in some way to make them different from their clan mates, usually resulting in proclivity for an extra discipline and the saddling of extra weakness. Some bloodlines are intentionally created, others are the results of accidents, but any vampire of suffiant blood potency can create a bloodline with time and experimentation.