Reginald Anthony Lewis (January 20, 1954- September 19, 2008 in New Orleans, Louisiana) was an American football defensive lineman who played three seasons in the National Football League for the New Orleans Saints. He was drafted in the 1976 NFL Draft by the San Francisco 49ers, but chose to play in the Canadian Football League for the Calgary Stampeders and the Toronto Argonauts, where he was a three time All-Star. Lewis played college football at San Diego State University.