HMS Tilbury was a 60-gun fourth rate ship of the line of the Royal Navy, built at Chatham Dockyard to the dimensions of the 1719 Establishment, and launched on 2 June 1733. The Tilbury was part of Vice-Admiral Edward Vernon's fleet and took part in the expedition to Cartagena de Indias during the War of Jenkin's Ear. Tilbury was accidentally burnt in 1742.