After the Red Flu pandemic, Immune leader Sean Ramsey began using the Achilles as his floating base of operations. The submarine came into conflict multiple times with the USS Nathan James, but never ended with either side sinking the other. In Cry Havoc Ramsey has the other Immunes form a blockade to force the Nathan James into battle with his sub while having a shore team set up an anti-ship missile battery in case the Nathan James gets close to shore. During the battle that follows, the Nathan James exhausts all of its weapons but four shells for its 5/62-inches Mark 45 Naval Gun which is a surface weapon. In response, Chandler decides to turn the battle into a surface fight and forces the Achilles to the surface by drawing it near shore where its too shallow for the sub to stay underwa