Hugh Sempill, 12th Lord Sempill (after 16 May 1688 – 25 November 1746) was a Scottish soldier. He was the fifth son of Francis Abercromby, Lord Glasfoord by his wife Anne Sempill, 9th Lady Sempill, daughter of Robert Sempill, 7th Lord Sempill. On 17 February 1727 he succeeded his brother as Lord Sempill, and that year he sold the estates of Elliotstoun and Castle Sempill, purchasing the estate of North Barr in 1741.