Bio 2 is the second spell on the Poison Magic Materia. It takes 5000 AP to learn, costs 36 MP to cast, has a base spell power equal to 1.3125x the base magic damage, and has a 48% chance of inflicting Poison. The enemies Flower Prong and Malboro, as well as the bosses Godo, Jenova∙SYNTHESIS, and Lost Number can use the spell against the party. Lost Number can only use the spell during its Magic form, while Jenova∙SYNTHESIS can only use the spell when both of its tentacles are alive. Flower Prong only uses the spell in its first and third forms.