The Midland Main Line is a major railway in the United Kingdom from London's St. Pancras station to the northern city of Sheffield via Luton, Bedford, Kettering, Leicester, East Midlands Parkway, Derby/Nottingham and Chesterfield. Since the closure of the rival Great Central Main Line in the 1960s, the Midland has been the only direct main-line rail link between London and the East Midlands and South Yorkshire.