When I adopted Greta on March 1, 2007, she was drinking and urinating 5+ cups of water a day. Her USG (urine specific gravity) was 1.001---water basically. At the shelter, she was receiving desmopressin drops (4 in each eye and nostril twice a day). I brought her home and started injecting the desmopressin subcutaneously. We started at 5u and were able to work down to 3u bid within a week (2.5U brought the heavy drinking back, so went back up to 3U). Her water consumption went down to less than 1/4 cup per 24 hours within a day of starting the injections. A week after starting this, Greta's USG had risen to 1.038---that of a normal cat!