Frank Kinney Holbrook (c.1874 in Tipton, Iowa – ??) was the first African American intercollegiate athlete at the University of Iowa and one of the first African Americans to participate on an American college varsity athletic squad. He played on the Iowa football team and lettered in both football and track in 1895 and 1896. He was Iowa's leading scorer in 1896 and led the Hawkeyes to their first football conference title in school history.