Lesa B. Roe is an American aerospace engineer who served as the Director of NASA Langley Research Center from 2005 to 2014. She previously served as the center's Deputy Director from June 2004 until being named Director in October 2005. She received her bachelor's degree in electrical engineering from the University of Florida, and her master's degree in electrical engineering from the University of Central Florida. Roe is the first female Director of NASA’s Langley Research Center. She has worked for NASA since 1987.