The Romans confronted the Samnites in the middle of the Liris river valley, sparking the Second, or Great Samnite War (326–304 BC), which lasted twenty years. In 328, the Romans, clearly looking for another fight with the Samnium, established a colony at Fregellae on the Liris and another Cales, earlier in 334 BC, the Samnites found that to be an unacceptable intrusion by Rome, but were too pre-occupied to respond at the time. The Samnites had to wait until after they finished their conflict with the Greek colony of Tarentum and its ally, King Alexander of Eprius.