The original lineup of Ani-Men (Ape-Man, Bird-Man, Cat-Man, Frog-Man) are recruited by a man named the Organizer. The Organizer is secretly Abner Jonas, a candidate for mayor of New York City, who sends the Ani-Men on missions to undermine the current administration. Daredevil defeats them and the Ani-Men and Organizer all go to prison. Later, Ape-Man, Bird-Man, and Cat-Man form a team called the "Unholy Three" and work with the Exterminator. Dragonfly continues her career as a villain, both on her own and as part of a team, such as the Femizons, and the Masters of Evil.